Speakers

Alexandria Wise Brown, PhD, is a global biopharmaceutical executive and neuroscientist with more than 20 years of experience spanning Medical Affairs, Clinical Development, Population Science, Digital Health, and Health Equity. As Therapeutic Area Lead for Population Science across Neuroscience and Ophthalmology at Roche, she partners with global clinical development leaders to integrate population science into therapeutic area strategies, advancing representative clinical research and evidence generation that strengthen scientific rigor, regulatory readiness, and patient outcomes worldwide. Her work focuses on embedding population-informed strategies throughout the drug development lifecycle, ensuring that clinical evidence reflects the biological, clinical, and social diversity of the patients medicines are intended to serve. Working across clinical science, regulatory, real-world data science, patient engagement, and global development teams, she helps shape disease area strategies, advance inclusive research, and strengthen evidence that supports equitable access to innovative therapies. Alexandria is a recognized thought leader at the intersection of artificial intelligence, digital health, population science, and inclusive clinical development. She is passionate about harnessing AI, advanced analytics, real-world evidence, and digital technologies to transform patient identification, clinical trial engagement, decentralized research, and evidence generation while ensuring research reflects the populations it is intended to serve. Throughout her career, Alexandria has pioneered innovative approaches to patient engagement and representative clinical research. As Medical Lead for the ALUMNI Alzheimer's disease study management team, she advanced community-based recruitment strategies, digitally enabled patient engagement, and innovative retention models to improve participation among historically underrepresented populations. She also helped lead the REACHED real-world evidence initiative, leveraging digital health technologies and real-world data to generate insights into disease progression and patient experiences in Alzheimer's disease that informed patient-centered evidence generation and clinical development. Previously, Alexandria served as Senior Medical Science Director within OMNI Scientific Strategy & Collaborations, where she led enterprise-wide scientific collaborations focused on health equity, healthcare systems, and innovative partnerships. She also developed Genentech's integrated customer experience measurement framework and led Diversity, Equity, and Inclusion strategy for the Alzheimer's Disease Medical Team, advancing representative clinical trial enrollment and inclusive research practices. Alexandria completed NIH T32 postdoctoral training at Columbia University and earned her PhD and MS in Neuroscience from the City University of New York Graduate Center.